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Ovarian cancer is the fourth most common cancer among women in the UK. Each year, there are around 6,900 new cases.

Ovarian cancer develops in cells of the ovary. The ovaries are two almond shaped organs located on either side of the uterus (womb). They produce eggs and the female hormones that both regulate the menstrual cycle and are responsible for female body characteristics. About 9 in 10 ovarian cancers form in the cells that line the ovaries.
 

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home > news Phase II Trials Investigating Oral PARP Inhibitor, Olaparib, In BRCA-Deficient Advanced Breast And Ovarian Cancer

Phase II Trials Investigating Oral PARP Inhibitor, Olaparib, In BRCA-Deficient Advanced Breast And Ovarian Cancer




"These encouraging data demonstrate the potential for olaparib to make a significant impact on the outcomes of patients with BRCA-deficient breast and ovarian cancer. AstraZeneca is fully evaluating the development of this drug in these diseases, and is exploring its potential in other populations of patients with cancers associated with defective DNA repair." Phase II data presented during the American Society of Clinical Oncology (ASCO) Congress for novel, oral anti-cancer treatment olaparib (AZD2281 / KU-0059436), demonstrate it is effective and well tolerated in women carrying the BRCA1 or BRCA2 gene mutation with advanced ovarian or breast cancer.1,2 Both studies have been selected for inclusion in the 'Best of ASCO' scientific prog...


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